The site will build the new Piccadilly Line trains for a planned refurbishment of that line to deliver more reliable, accessible and faster journeys across London.
Ms Haigh will attend Siemens' Rail Village to celebrate the formal opening of its new site.
Siemens Mobility is also announcing up to a further £40 million towards a new bogie assembly and service centre which will create up to 200 extra jobs.
The Government say the hub has been made possible by funding settlements with Transport for London (TfL) that has given Siemens the confidence to invest in the site.
The opening comes ahead of the Government's International Investment Summit on October 14, which will bring together companies and major investors as Labour pitches Britain to businesses.
As part of this drive, the Transport Secretary says she is working to end the "boom and bust" approach to rail manufacturing by delivering a long-term industrial strategy for rolling stock.
RECOMMENDED READING:
- Siemens Mobility takes on 35 staff as part of Goole expansion
- Siemens London Piccadilly line trains will be built in Goole
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