The road is blocked with queueing traffic on the A64 westbound between Hull Road Grimston Bar interchange and the A19 Fulford Road interchange.
Steve Harris, owner of Anytime Travel minibuses that operate in York, has reported two mile queues on the road.
He also told The Press that Fire crews, the police and the ambulance service were at the scene.
The ambulance service have issued a statement on the incident, they said: "We received an emergency call at 8.48am on Thursday morning to report a collision between two vehicles on the A64 between Grimston Bar and Fulford.
YOU’LL FIND MORE ON THIS STORY AND OTHERS AT www.yorkpress.co.uk OR PICK UP YOUR COPY OF THE NEWSPAPER ITSELF AVAILABLE SIX DAYS A WEEK AT YOUR LOCAL NEWSAGENT
Patience Series Two Release Date Announced
Christmas Miracle Reunites Brothers After 81 Years
Ultra Lux Seats at Vue Cinema at Clifton Moor in York
York Gin Wins 'Glass Champion' Award for Sustainability
102 Year Old Receives Surprise Message from Dance Star
Lord Mayor's Commendation Scheme
Gold for second year running for York business
York Minster saving energy on rooftop solar system
