The county's police force has said they are at the scene of the crash on the A19 at North Kilvington, north of Thirsk.
Reports show it to be near the junctions with the A168 and A61.
It has been described as a serious incident.
"Highways have put in place a road closure and are diverting traffic from the scene," a spokesperson said.
They advised motorists to avoid the area.
YOU’LL FIND MORE ON THIS STORY AND OTHERS AT www.yorkpressd.co.uk OR PICK UP YOUR COPY OF THE NEWSPAPER ITSELF AVAILABLE SIX DAYS A WEEK AT YOUR LOCAL NEWSAGENT
AN historic estate in North Yorkshire which includes a country house and a well-known ruined abbey has gone on the market for £25 million.
